Launched in March 2013, the Model-Driven European Paediatric Digital Repository (MD PAEDIGREE) project is a clinically-driven concerted effort between seven clinical centres, four European and one US industrial partners, two consultancies, and nine research partners within the Virtual Physiological Human (VPH) community. The project will build upon the experience obtained and tools developed during earlier projects (namely Health-e-Child and Sim-e-Child) and will aim at validating and advancing patient-specific, computer-based predictive models of six paediatric pathologies (cardiomyopathy, cardiovascular disease risk in young obese patients, juvenile idiopathic arthritis, Type 3 spinal muscular atrophy, hemiplegic cerebral palsy, and Duchenne dystrophy) beyond the current state of the art such that they evolve into a mature piece of technology that will be accepted by healthcare professionals.
Of special interest to the Haute Ecole Spécialisée de Suisse Occidentale is the development of a novel digital repository that will implement the Service-Oriented Knowledge Utility (SOKU) vision during the course of MD PAEDIGREE. The repository will form the basis of an innovative model-driven Infostructure that will enable healthcare professionals with a web-based tool to access a vast amount of heterogeneous and multimodal patient data at the point of care. That information, coupled with patient-specific information, can subsequently be used to make more informed decisions regarding the treatment that will lead to the best possible outcome for a particular patient. Universal use of the repository by clinicians for accessing, analyzing, evaluating, enhancing and sharing biomedical data of all forms is the ultimate goal of the project.
The partners involved in MD PAEDIGREE are:
Clinical centres:
– Ospedale Pediatrico Bambino Gesu
– University College London
– Istituto Giannina Gaslini
– Johns Hopkins University
– Katholieke Universiteit Leuven
– Stichting VU-VUmc
– Universitair Medisch Centrum Utrecht
Industrial partners:
– BMR Genomics (EU)
– Maat France (EU)
– Motek Medical BV (EU)
– Siemens AG (EU)
– Siemens Corporate Research (US)
Consulting firms:
– Empirica
– Lynkeus
VPH research community:
– Fraunhofer Institut für Graphische Datenverarbeitung
– Haute Ecole Spécialisée de Suisse Occidentale
– INRIA
– National and Kapodistrian University of Athens
– TU Delft
– TU München
– Universita Degli Studi Di Roma La Sapienza
– Universitatea Transilvania Din Brasov
– University of Sheffield