Article published on Whole Slide Images registration

Our work on Whole Slide Images (WSIs) registration was published in Computer Methods and Programs in Biomedicine:

RegWSI: Whole slide image registration using combined deep feature- and intensity-based methods: Winner of the ACROBAT 2023 challenge“, by M. Wodzinski, N. Marini, M. Atzori, and H. Müller

In this article, we introduce a new method dedicated to automatic registration of WSIs. The proposed method has superior generalizability and does not require any re-training or fine-tuning to particular dataset. The quantitative results are very accurate, and the algorithm is the best registration method on the ACROBAT and HyReCo datasets.

The source code is released and included in the DeeperHistReg framework, allowing end-users to use it in their research.

Exemplary registration pairs from the ACROBAT, ANHIR, and HyReCo datasets. Note the clinical quality of the ACROBAT samples (without any initial preprocessing and numerous artifacts), large initial misalignment in the ANHIR dataset, and the good quality of the HyReCo samples.